Lateral Hypothalamic Control of Energy Balance (Colloquium Series on Integrated Systems Physiology: From Molecule to Function to Disease)

Reviews the essential role of the lateral hypothalamic area (LHA) for the control of body weight, from its historical description as a "feeding centre" to the current view of this LHA as a cellularly heterogeneous hub that regulates multiple aspects of physiology to influence body weight. The authors also evaluate how specific LHA populations coordinate certain metabolic cues and behaviours.