The Endothelium, Part II : EDHF-Mediated Responses ''The Classical Pathway (Colloquium Series on Integrated Systems Physiology)

The endothelium controls vascular tone by releasing various vasoactive substances. Additionally, another pathway associated with the hyperpolarization of both endothelial and vascular smooth muscle cells contributes also to endothelium-dependent relaxations (EDHF-mediated responses).