§16§This book provides BoNT treatment menus for symptom-oriented therapy in 14 different disease categories.Each chapter starts with a brief description of the disease and its current treatment followed by an evidenced-based upon the published assertions of the Therapeutic Subcommittee of the American Academy of Neurology. §04§Molecular structure, mechanism of function, toxin serotypes, immunogenicity, and safety issues.- Parkinson's disease. Indications: Sialorrea, blepharospasm, focal painful dystonia of hands or feet, rigidity.- Atypical Parkinson Syndromes and other neurodegenerative disorders: Sialorrea, Hyperhidrosis, Blepharospasm, Focal painful dystonia, Rigidity.- Multiple Sclerosis. Indications: Spasticity, Focal dystonia, Neuropathic pain (trigeminal neuralgia).- Stroke- Indications: Post-stroke spasticity, Painful focal dystonia, Sialorrhea , Hemifacial spasms.- Cerebral palsy- Indications: Rigidity, Spasticity, Painful dystonia, Sialorrhea.- Orthopedic disorders- Indications: local painful §04§graine and other headaches.- Neuropathic pains (post-herpetic neuralgia, post-traumatic neuralgia, §02§The editor is Professor Emeritus of Neurology at the Yale University School of Medicine. He was director of the botulinum toxin treatment program at Yale from January 2005 to September 2015. His experience with botulinum toxin therapy of a large volume of patients extends over 25 years, and he has written extensively on the role of botulinum toxin therapy in clinical medicine.
